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Nikon NIKKOR Z 100-400mm f/4.5-5.6 VR S vs Nikon NIKKOR Z 180-600mm f/5.6-6.3 VR

Both are Nikon Z mount zooms for sports & action and telephoto — here's how the specs differ and which to pick. Every spec is from the manufacturer's own catalog.

Last verified 2026-06-21 · Nikon Z mount · prices change — check the retailer

SpecNikon NIKKOR Z 100-400mm f/4.5-5.6 VR SNikon NIKKOR Z 180-600mm f/5.6-6.3 VR
Focal length100-400mm180-600mm
Max aperturef/4.5-5.6f/5.6-6.3
Typezoomzoom
Coveragefull-framefull-frame
MountNikon ZNikon Z

Which should you buy?

Where to buy

Check the Nikon NIKKOR Z 100-400mm f/4.5-5.6 VR S price on Amazon →

Check the Nikon NIKKOR Z 180-600mm f/5.6-6.3 VR price on Amazon →

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FAQ

What's the difference between the Nikon NIKKOR Z 100-400mm f/4.5-5.6 VR S and the Nikon NIKKOR Z 180-600mm f/5.6-6.3 VR?
The Nikon NIKKOR Z 100-400mm f/4.5-5.6 VR S is 100-400mm f/4.5-5.6 zoom, full-frame; the Nikon NIKKOR Z 180-600mm f/5.6-6.3 VR is 180-600mm f/5.6-6.3 zoom, full-frame. Both fit the Nikon Z mount.

Which is better in low light, the Nikon NIKKOR Z 100-400mm f/4.5-5.6 VR S or the Nikon NIKKOR Z 180-600mm f/5.6-6.3 VR?
The Nikon NIKKOR Z 100-400mm f/4.5-5.6 VR S — its f/4.5-5.6 maximum aperture lets in more light and gives more background blur than the f/5.6-6.3 of the other.

Do the Nikon NIKKOR Z 100-400mm f/4.5-5.6 VR S and Nikon NIKKOR Z 180-600mm f/5.6-6.3 VR fit the same camera?
Yes — both are Nikon Z mount lenses, so they fit Nikon Z series (Z6/Z7/Z8/Z9 full-frame, Z50/Zfc APS-C).

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